Chemical Libraries

BioMol Libraries

Bioactive lipids, 204 compounds. endo-cannabinoid, 60 compounds, ion channel, 72 compounds, enzyme inhibitors, 84 compounds and phosphatase and kinase inhibitors, orphan ligands, 84 compounds. This library serves primarily for assay validation.

FDA Approved Drug Library

A unique collection of 1120 high-purity chemical compounds (all off patent)
carefully selected for:

• Structural diversity
• Broad spectrum covering several therapeutic areas
  (from neuropsychiatry to cardiology, immunology,
  anti-inflammatory, analgesia and more)
• Known safety and bioavailability in humans

Microsource Spectrum Collection

2000 biologically active and structurally diverse compounds from our libraries of known drugs, experimental bioactives, and pure natural products.

Druggable Compound Set

A set of about 8000 compounds which are targeted at kinases, protease, ion channels and GPCR's. These compounds are designed to match our siRNA efforts which are based on sets of siRNA's for the druggable human and mouse genome.

Lead Like Compound Set

This set of 20,000 compounds has been custom tailored for us for lead likeness. The compounds in this set are not to be found in any of the traditional "Russian" collections

Chemically Diverse Library (Combichem Library)

ChemBridge DiverSet, 30,000 chemically diverse small molecules.

siRNA Libraries

We just acquired sets of siRNA's for the druggable genome of mouse and human. Shortly, we will offer a full range of screens using this technology. We envision to use this technology for the identification of the targets of compounds found in conventional HTS screens as well as for answering basic research questions.

Yeast Knockout Collection

A genome wide set of non-essential knockout mutants of yeast is available for screening in both mating types (alpha and A). The strain collections have been condensed into 384 well plates to facilitate high throughput.

UCLA in-house Collection

Various professors have donated their compounds to our in-house collection and so far we have collected about 5000 compounds. These libraires are extremely diverse and range from natural products to compounds which have been synthesized using diversity-oriented synthesis.