Publication List
2013
High Throughput Screening of Small Molecules Identifies Hepcidin Antagonists, Fung E, Sugianto P, Hsu J, Damoiseaux R, Ganz T, Nemeth E, Mol Pharmacol. 2013 Jan 9. [Epub ahead of print]
2012
Dantrolene enhances antisense-mediated exon skipping in human and mouse models of duchenne muscular dystrophy, Kendall GC, Mokhonova EI, Moran M, Sejbuk NE, Wang DW, Silva O, Wang RT, Martinez L, Lu QL, Damoiseaux R, Spencer MJ, Nelson SF, Miceli MC, Sci Transl Med. 2012 Dec 12;4(164):164ra160
Zebrafish: An In Vivo Model for Nano EHS Studies, Lin S, Zhao Y, Nel AE, Lin S, Small. 2012 Dec 3. doi: 10.1002/smll.201202115. [Epub ahead of print]
Genome-wide assessment in Escherichia coli reveals time-dependent nanotoxicity paradigms, Reyes VC, Li M, Hoek EM, Mahendra S, Damoiseaux R, ACS Nano. 2012 Nov 27;6(11):9402-15.
Size influences the cytotoxicity of poly (lactic-co-glycolic acid) (PLGA) and titanium dioxide (TiO(2)) nanoparticles, Xiong S, George S, Yu H, Damoiseaux R, France B, Ng KW, Loo JS, Arch Toxicol. 2012 Sep 16.
Size of TiO(2) nanoparticles influences their phototoxicity: an in vitro investigation, Xiong S, George S, Ji Z, Lin S, Yu H, Damoiseaux R, France B, Ng KW, Loo SC,Arch Toxicol. 2013 Jan;87(1):99-109
High-throughput screening for bioactive molecules using primary cell culture of transgenic zebrafish embryos, Huang H, Lindgren A, Wu X, Liu NA, Lin S, Cell Rep. 2012 Sep 27;2(3):695-704
Fluoxetine is a potent inhibitor of coxsackievirus replication, Zuo J, Quinn KK, Kye S, Cooper P, Damoiseaux R, Krogstad P, Antimicrob Agents Chemother. 2012 Sep;56(9):4838-44
Quantitative detection of PfHRP2 in saliva of malaria patients in the Philippines, Fung AO, Damoiseaux R, Grundeen S, Panes JL, Horton DH, Judy JW, Moore TB, Malar J. 2012 May 25;11:175.
Automated phenotype recognition for zebrafish embryo based in vivo high throughput toxicity screening of engineered nano-materials, Liu R, Lin S, Rallo R, Zhao Y, Damoiseaux R, Xia T, Lin S, Nel A, Cohen Y, PLoS One. 2012;7(4):e35014.
Use of metal oxide nanoparticle band gap to develop a predictive paradigm for oxidative stress and acute pulmonary inflammation, Zhang H, Ji Z, Xia T, Meng H, Low-Kam C, Liu R, Pokhrel S, Lin S, Wang X, Liao YP, Wang M, Li L, Rallo R, Damoiseaux R, Telesca D, Mädler L, Cohen Y, Zink JI, Nel AE, ACS Nano. 2012 May 22;6(5):4349-68
Combination of Rad001 (everolimus) and propachlor synergistically induces apoptosis through enhanced autophagy in prostate cancer cells, Tai S, Sun Y, Liu N, Ding B, Hsia E, Bhuta S, Thor RK, Damoiseaux R, Liang C, Huang J, Mol Cancer Ther. 2012 Jun;11(6):1320-31
Genome-wide Bacterial Toxicity Screening Uncovers the Mechanisms of Toxicity of Cationic Polystyrene Nanomaterials, Ivask A, Suarez E, Patel T, Boren D, Ji Z, Holden PA, Telesca D, Damoiseaux R, Bradley KA, Godwin HA, Environ Sci Technol. 2011 Dec
2011
A molecular screening approach to identify and characterize inhibitors of glioblastoma multiforme stem cells, Visnyei K, Onodera H, Damoiseaux R, Saigusa K, Petrosyan S, De Vries D, Ferrari DB, Saxe J, Panosyan E, Masterman-Smith M, Mottahedeh J, Bradley KA, Huang J, Sabatti C, Nakano I, Kornblum HI, Mol Cancer Ther. 2011 Aug 22
High Content Screening in Zebrafish Speeds up Hazard Ranking of Transition Metal Oxide Nanoparticles, Lin S, Zhao Y, Xia T, Meng H, Ji Z, Liu R, George S, Xiong S, Wang X, Zhang H, Pokhrel S, Mädler L, Damoiseaux R, Lin S, Nel AE, ACS Nano, 2011 Aug 2
High throughput screening of small molecule libraries for modifiers of radiation responses, Kim K, Damoiseaux R, Norris AJ, Rivina L, Bradley K, Jung ME, Gatti RA, Schiestl RH, McBride WH, Int J Radiat Biol. 2011 Aug;87(8):839-4
Use of a high-throughput screening approach coupled with in vivo zebrafish embryo screening to develop hazard ranking for engineered nanomaterials, George S, Xia T, Rallo R, Zhao Y, Ji Z, Lin S, Wang X, Zhang H, France B, Schoenfeld D, Damoiseaux R, Liu R, Lin S, Bradley KA, Cohen Y, Nel AE, ACS Nano. 2011 Mar 22;5(3):1805-17
No time to lose-high throughput screening to assess nanomaterial safety, Damoiseaux R, George S, Li M, Pokhrel S, Ji Z, France B, Xia T, Suarez E, Rallo R, Mädler L, Cohen Y, Hoek EM, Nel A, Nanoscale. 2011 Feb 7
Metabolic imaging allows early prediction of response to vandetanib, Walter MA, Benz MR, Hildebrandt IJ, Laing RE, Hartung V, Damoiseaux RD, Bockisch A, Phelps ME, Czernin J, Weber WA, J Nucl Med. 2011 Feb;52(2):231-40
Stability, bioavailability, and bacterial toxicity of ZnO and iron-doped ZnO nanoparticles in aquatic media.Li M, Pokhrel S, Jin X, Mädler L, Damoiseaux R, Hoek EM, Environ Sci Technol. 2011 Jan 15;45(2):755-61
2010
Yeast DEL assay detects protection against radiation-induced cytotoxicity and genotoxicity: adaptation of a microtiter plate version, Hafer K, Rivina Y, Schiestl RH, Radiat Res. 2010 Dec;174(6):719-26
High-content screening for biofilm assays, Peng F, Hoek EM, Damoiseaux R., J Biomol Screen. 2010 Aug;15(7):748-54
Chemical genetics screen for enhancers of rapamycin identifies a specific inhibitor of an SCF family E3 ubiquitin ligase. Aghajan M, Jonai N, Flick K, Fu F, Luo M, Cai X, Ouni I, Pierce N, Tang X, Lomenick B, Damoiseaux R, Hao R, Del Moral PM, Verma R, Li Y, Li C, Houk KN, Jung ME, Zheng N, Huang L, Deshaies RJ, Kaiser P, Huang J., Nat Biotechnol. 2010 Jul;28(7):738-42
A broad-spectrum antiviral targeting entry of enveloped viruses, Wolf MC, Freiberg AN, Zhang T, Akyol-Ataman Z, Grock A, Hong PW, Li J, Watson NF, Fang AQ, Aguilar HC, Porotto M, Honko AN, Damoiseaux R, Miller JP, Woodson SE, Chantasirivisal S, Fontanes V, Negrete OA, Krogstad P, Dasgupta A, Moscona A, Hensley LE, Whelan SP, Faull KF, Holbrook MR, Jung ME, Lee B, Proc Natl Acad Sci U S A. 2010 Feb 16;107(7):3157-62. Epub 2010 Jan 28
Integrated pathways for neutrophil recruitment and inflammation in leprosy, Lee DJ, Li H, Ochoa MT, Tanaka M, Carbone RJ, Damoiseaux R, Burdick A, Sarno EN, Rea TH, Modlin RL, J Infect Dis. 2010 Feb 15;201(4):558-69
Use of a rapid cytotoxicity screening approach to engineer a safer zinc oxide nanoparticle through iron doping, George S, Pokhrel S, Xia T, Gilbert B, Ji Z, Schowalter M, Rosenauer A, Damoiseaux R, Bradley KA, Mädler L, Nel AE, ACS Nano. 2010 Jan 26;4(1):15-29
Rottlerin stimulates apoptosis in pancreatic cancer cells through interactions with proteins of the Bcl-2 family, Ohno I, Eibl G, Odinokova I, Edderkaoui M, Damoiseaux RD, Yazbec M, Abrol R, Goddard WA 3rd, Yokosuka O, Pandol SJ, Gukovskaya AS, Am J Physiol Gastrointest Liver Physiol. 2010 Jan;298(1):G63-73
2009
High-throughput screening identifies two classes of antibiotics as radioprotectors: tetracyclines and fluoroquinolones, Kim K, Pollard JM, Norris AJ, McDonald JT, Sun Y, Micewicz E, Pettijohn K, Damoiseaux R, Iwamoto KS, Sayre JW, Price BD, Gatti RA, McBride WH, Clin Cancer Res. 2009 Dec 1;15(23):7238-45
Discovery and structure-activity relationship analysis of Staphylococcus aureus sortase A inhibitors, Suree N, Yi SW, Thieu W, Marohn M, Damoiseaux R, Chan A, Jung ME, Clubb RT, Bioorg Med Chem. 2009 Oct 15;17(20):7174-85.
Nonaminoglycoside compounds induce readthrough of nonsense mutations, Du L, Damoiseaux R, Nahas S, Gao K, Hu H, Pollard JM, Goldstine J, Jung ME, Henning SM, Bertoni C, Gatti RA, J Exp Med. 2009 Sep 28;206(10):2285-97. Epub 2009 Sep 21.PMID: 19770270
Integrated chemical genomics reveals modifiers of survival in human embryonic stem cells, Damoiseaux R, Sherman SP, Alva JA, Peterson C, Pyle AD, Stem Cells. 2009 Mar;27(3):533-42
Ion channel and toxin measurement using a high throughput lipid membrane platformPoulos JL, Jeon TJ, Damoiseaux R, Gillespie EJ, Bradley KA, Schmidt JJ, Biosens Bioelectron. 2009 Feb 15;24(6):1806-10
2008
A high-throughput screening strategy identifies cardiotonic steroids as alternative splicing modulators.Stoilov P, Lin CH, Damoiseaux R, Nikolic J, Black DL, Proc Natl Acad Sci U S A. 2008 Aug 12;105(32):11218-23
Regulation of Kaposi's sarcoma-associated herpesvirus reactivation by dopamine receptor-mediated signaling pathways, Lee S, Deng H, Yu F, Melega WP, Damoiseaux R, Bradley KA, Sun R, J Acquir Immune Defic Syndr. 2008 Aug 15;48(5):531-40. Erratum in: J Acquir Immune Defic Syndr. 2008 Oct 1;49(2):235
2007
Development of a microtiter plate version of the yeast DEL assay amenable to high-throughput toxicity screening of chemical libraries, Hontzeas N, Hafer K, Schiestl RH, Mutat Res. 2007 Dec 1;634(1-2):228-34
The small molecule harmine is an antidiabetic cell-type-specific regulator of PPARgamma expression, Waki H, Park KW, Mitro N, Pei L, Damoiseaux R, Wilpitz DC, Reue K, Saez E, Tontonoz P, Cell Metab. 2007 May;5(5):357-70
Amiodarone and bepridil inhibit anthrax toxin entry into host cells, Sanchez AM, Thomas D, Gillespie EJ, Damoiseaux R, Rogers J, Saxe JP, Huang J, Manchester M, Bradley KA, Antimicrob Agents Chemother. 2007 Jul;51(7):2403-11. Epub 2007 May 7.
2006
Mycophenolic acid is a potent inhibitor of angiogenesis, Wu X, Zhong H, Song J, Damoiseaux R, Yang Z, Lin S, Arterioscler Thromb Vasc Biol. 2006 Oct;26(10):2414-6..
Cell-based chemical genetic screen identifies damnacanthal as an inhibitor of HIV-1 Vpr induced cell death, Kamata M, Wu RP, An DS, Saxe JP, Damoiseaux R, Phelps ME, Huang J, Chen IS, Biochem Biophys Res Commun. 2006 Sep 29;348(3):1101-6