Publication List

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Self-Organized Cerebral Organoids with Human-Specific Features Predict Effective Drugs to Combat Zika Virus Infection.

Watanabe M, Buth JE, Vishlaghi N, de la Torre-Ubieta L, Taxidis J, Khakh BS, Coppola G, Pearson CA, Yamauchi K, Gong D, Dai X, Damoiseaux R, Aliyari R, Liebscher S, Schenke-Layland K, Caneda C, Huang EJ, Zhang Y, Cheng G, Geschwind DH, Golshani P, Sun R, Novitch BG. Cell Rep. 2017 Oct 10;21(2):517-532. doi: 10.1016/j.celrep.2017.09.047.


Exploiting drug addiction mechanisms to select against MAPKi-resistant melanoma.

Hong A, Moriceau G, Sun L, Lomeli S, Piva M, Damoiseaux R, Holmen SL, Sharpless NE, Hugo W, Lo RS, Cancer Discov. 2017 Sep 18. pii: CD-17-0682. doi: 10.1158/2159-8290.CD-17-0682. [Epub ahead of print]


Gα12 Facilitates Carbachol-Induced Shortening in Human Airway Smooth Muscle By Modulating Phosphoinositide 3-Kinase-Mediated Activation In A RhoA-Dependent Manner.

Yoo EJ, Cao G, Koziol-White CJ, Ojiaku CA, Sunder K, Jude JA, Michael JV, Lam H, Pushkarsky I, Damoiseaux R, Di Carlo D, Ahn K, An SS, Penn RB, Panettieri RA Jr., Br J Pharmacol. 2017 Sep 17. doi: 10.1111/bph.14040. [Epub ahead of print]

Computational Cell Cycle Profiling of Cancer Cells for Prioritizing FDA-Approved Drugs with Repurposing Potential.

Lo YC, Senese S, France B, Gholkar AA, Damoiseaux R, Torres JZ, Sci Rep. 2017 Sep 12;7(1):11261. doi: 10.1038/s41598-017-11508-2.

A comparative assessment of antiproliferative properties of resveratrol and ethanol leaf extract of Anogeissus leiocarpus (DC) Guill and Perr against HepG2 hepatocarcinoma cells.

Olugbami JO, Damoiseaux R, France B, Onibiyo EM, Gbadegesin MA, Sharma S, Gimzewski JK, Odunola OA. BMC Complement Altern Med. 2017 Aug 2;17(1):381. doi: 10.1186/s12906-017-1873-2.

Direct quantification of gamma H2AX by cell-based high throughput screening for evaluation of genotoxicity of pesticides in a human thyroid cell lines.

Hershman JM, France B, Hon K, Damoiseaux R, Environ Mol Mutagen. 2017 Aug;58(7):522-528. doi: 10.1002/em.22103. Epub 2017 Jun 22.

4-(Nitrophenylsulfonyl)piperazines mitigate radiation damage to multiple tissues.

Micewicz ED, Kim K, Iwamoto KS, Ratikan JA, Cheng G, Boxx GM, Damoiseaux RD, Whitelegge JP, Ruchala P, Nguyen C, Purbey P, Loo J, Deng G, Jung ME, Sayre JW, Norris AJ, Schaue D, McBride WH, PLoS One. 2017 Jul 21;12(7):e0181577. doi: 10.1371/journal.pone.0181577. eCollection 2017

Interferon Receptor Signaling Pathways Regulating PD-L1 and PD-L2 Expression.

Garcia-Diaz A, Shin DS, Moreno BH, Saco J, Escuin-Ordinas H, Rodriguez GA, Zaretsky JM, Sun L, Hugo W, Wang X, Parisi G, Saus CP, Torrejon DY, Graeber TG, Comin-Anduix B, Hu-Lieskovan S, Damoiseaux R, Lo RS, Ribas A, Cell Rep. 2017 May 9;19(6):1189-1201. doi: 10.1016/j.celrep.2017.04.031

When more is less: Emergent suppressive interactions in three-drug combinations.

Beppler C, Tekin E, White C, Mao Z, Miller JH, Damoiseaux R, Savage VM, Yeh PJ, BMC Microbiol. 2017 May 6;17(1):107. doi: 10.1186/s12866-017-1017-3.

Atomic force microscopy correlates antimetastatic potentials of HepG2 cell line with its redox/energy status: effects of curcumin and Khaya senegalensis.

Olugbami JO, Damoiseaux R, France B, Gbadegesin MA, Stieg AZ, Sharma S, Odunola OA, Gimzewski JK, J Integr Med. 2017 May;15(3):214-230. doi: 10.1016/S2095-4964(17)60337-6.

Engineering a Thermostable Keto Acid Decarboxylase Using Directed Evolution and Computationally Directed Protein Design.

Soh LMJ, Mak WS, Lin PP, Mi L, Chen FY, Damoiseaux R, Siegel JB, Liao JC, ACS Synth Biol. 2017 Apr 21;6(4):610-618. doi: 10.1021/acssynbio.6b00240. Epub 2017 Jan 11.

Adaptation of a Genetic Screen Reveals an Inhibitor for Mitochondrial Protein Import Component Tim44.

Miyata N, Tang Z, Conti MA, Johnson ME, Douglas CJ, Hasson SA, Damoiseaux R, Chang CA, Koehler CM, J Biol Chem. 2017 Mar 31;292(13):5429-5442. doi: 10.1074/jbc.M116.770131. Epub 2017 Feb 6.


Inhibition of PI3K promotes dilation of human small airways in a rho kinase-dependent manner.

Koziol-White CJ, Yoo EJ, Cao G, Zhang J, Papanikolaou E, Pushkarsky I, Andrews A, Himes BE, Damoiseaux RD, Liggett SB, Di Carlo D, Kurten RC, Panettieri RA Jr, Br J Pharmacol. 2016 Sep;173(18):2726-38. doi: 10.1111/bph.13542. Epub 2016 Aug 3.

3D Chemical Similarity Networks for Structure-Based Target Prediction and Scaffold Hopping.

Lo YC, Senese S, Damoiseaux R, Torres JZ, ACS Chem Biol. 2016 Aug 19;11(8):2244-53. doi: 10.1021/acschembio.6b00253. Epub 2016 Jun 20.

Characterization and evolution of an activator-independent methanol dehydrogenase from Cupriavidus necator N-1. Wu TY, Chen CT, Liu JT, Bogorad IW, Damoiseaux R, Liao JC, Appl Microbiol Biotechnol. 2016 Feb 5. [Epub ahead of print]


Discovery of Structurally Diverse Small-Molecule Compounds with Broad Antiviral Activity against Enteroviruses. Zuo J, Kye S, Quinn KK, Cooper P, Damoiseaux R, Krogstad P, Antimicrob Agents Chemother. 2015 Dec 28;60(3):1615-26. doi: 10.1128/AAC.02646-15.

A high-throughput screen of inactive X chromosome reactivation identifies the enhancement of DNA demethylation by 5-aza-2'-dC upon inhibition of ribonucleotide reductase.Minkovsky A, Sahakyan A, Bonora G, Damoiseaux R, Dimitrova E, Rubbi L, Pellegrini M, Radu CG, Plath K, Epigenetics Chromatin. 2015 Oct 13;8:42. doi: 10.1186/s13072-015-0034-4. eCollection 2015.

Copper status of exposed microorganisms influences susceptibility to metallic nanoparticles. Reyes VC, Spitzmiller MR, Hong-Hermesdorf A, Kropat J, Damoiseaux RD, Merchant SS, Mahendra S, Environ Toxicol Chem. 2015 Sep 21. doi: 10.1002/etc.3254.

Novel Arenavirus Entry Inhibitors Discovered by Using a Minigenome Rescue System for High-Throughput Drug Screening, Rathbun JY, Droniou ME, Damoiseaux R, Haworth KG, Henley JE, Exline CM, Choe H, Cannon PM, J. Virol. 2015 Aug;89(16):8428-43. doi: 10.1128/JVI.00997-15. Epub 2015 Jun 3.

Glucocorticoids suppress renal cell carcinoma progression by enhancing Na,K-ATPase beta-1 subunit expression. Huynh TP, Barwe SP, Lee SJ, McSpadden R, Franco OE, Hayward SW, Damoiseaux R, Grubbs SS, Petrelli NJ, Rajasekaran AK, PLoS One. 2015 Apr 2;10(4):e0122442. doi: 10.1371/journal.pone.0122442. eCollection 2015.

Large-scale chemical similarity networks for target profiling of compounds identified in cell-based chemical screens. Lo YC, Senese S, Li CM, Hu Q, Huang Y, Damoiseaux R, Torres JZ, PLoS Comput Biol. 2015 Mar 31;11(3):e1004153. doi: 10.1371/journal.pcbi.1004153. eCollection 2015 Mar.

Identification of small molecules that disrupt signaling between ABL and its positive regulator RIN1, Ting PY, Damoiseaux R, Titz B, Bradley KA, Graeber TG, Fernández-Vega V, Bannister TD, Chase P, Nair R, Scampavia L, Hodder P, Spicer TP, Colicelli J, PLoS One. 2015 Mar 26;10(3):e0121833. doi: 10.1371/journal.pone.0121833. eCollection 2015


Chemical dissection of the cell cycle: probes for cell biology and anti-cancer drug development, Senese S, Lo YC, Huang D, Zangle TA, Gholkar AA, Robert L, Homet B, Ribas A, Summers MK, Teitell MA, Damoiseaux R, Torres JZ, Cell Death Dis. 2014 Oct 16;5:e1462. doi: 10.1038/cddis.2014.420

Cytolethal distending toxins require components of the ER-associated degradation pathway for host cell entry, Eshraghi A, Dixon SD, Tamilselvam B, Kim EJ, Gargi A, Kulik JC, Damoiseaux R, Blanke SR, Bradley KA, PLoS Pathog. 2014 Jul 31;10(7):e1004295. doi: 10.1371/journal.ppat.1004295. eCollection 2014 Jul.

UCLA's Molecular Screening Shared Resource: enhancing small molecule discovery with functional genomics and new technology, Damoiseaux R, Comb Chem High Throughput Screen. 2014 May;17(4):356-68.

Calcium signaling via Orai1 is essential for induction of the nuclear orphan receptor pathway to drive Th17 differentiation, Kim KD, Srikanth S, Tan YV, Yee MK, Jew M, Damoiseaux R, Jung ME, Shimizu S, An DS, Ribalet B, Waschek JA, Gwack Y, J Immunol. 2014 Jan 1;192(1):110-22. doi: 10.4049/jimmunol.1302586. Epub 2013 Dec 4

Toxicity Mechanisms in Escherichia coli Vary for Silver Nanoparticles and Differ from Ionic Silver, Ivask A, Elbadawy A, Kaweeteerawat C, Boren D, Fischer H, Ji Z, Chang CH, Liu R, Tolaymat T, Telesca D, Zink JI, Cohen Y, Holden PA, Godwin HA, ACS Nano. 2014 Jan 28;8(1):374-86. doi: 10.1021/nn4044047. Epub 2013 Dec 24.


Genome-wide RNAi high-throughput screen identifies proteins necessary for the AHR-dependent induction of CYP1A1 by 2,3,7,8-tetrachlorodibenzo-p-dioxin, Solaimani P, Damoiseaux R, Hankinson O, Toxicol Sci. 2013 Nov;136(1):107-19. doi: 10.1093/toxsci/kft191. Epub 2013 Aug 31

Development of new deoxycytidine kinase inhibitors and noninvasive in vivo evaluation using positron emission tomography, Murphy JM, Armijo AL, Nomme J, Lee CH, Smith QA, Li Z, Campbell DO, Liao HI, Nathanson DA, Austin WR, Lee JT, Darvish R, Wei L, Wang J, Su Y, Damoiseaux R, Sadeghi S, Phelps ME, Herschman HR, Czernin J, Alexandrova AN, Jung ME, Lavie A, Radu CG, J Med Chem. 2013 Sep 12;56(17):6696-708. doi: 10.1021/jm400457y. Epub 2013 Aug 15

Selective inhibitor of endosomal trafficking pathways exploited by multiple toxins and viruses, Gillespie EJ, Ho CL, Balaji K, Clemens DL, Deng G, Wang YE, Elsaesser HJ, Tamilselvam B, Gargi A, Dixon SD, France B, Chamberlain BT, Blanke SR, Cheng G, de la Torre JC, Brooks DG, Jung ME, Colicelli J, Damoiseaux R, Bradley KA, Proc Natl Acad Sci U S A. 2013 Dec 10;110(50):E4904-12. doi: 10.1073/pnas.1302334110. Epub 2013 Nov 4

A new series of small molecular weight compounds induce read through of all three types of nonsense mutations in the ATM gene, Du L, Jung ME, Damoiseaux R, Completo G, Fike F, Ku JM, Nahas S, Piao C, Hu H, Gatti RA, Mol Ther. 2013 Sep;21(9):1653-60. doi: 10.1038/mt.2013.150. Epub 2013 Jun 18

A broadly applicable high-throughput screening strategy identifies new regulators of Dlg4 (Psd-95) alternative splicing, Zheng S, Damoiseaux R, Chen L, Black DL, Genome Res. 2013 Jun;23(6):998-1007. doi: 10.1101/gr.147546.112. Epub 2013 May 1

A small molecule inhibitor of redox-regulated protein translocation into mitochondria, Dabir DV, Hasson SA, Setoguchi K, Johnson ME, Wongkongkathep P, Douglas CJ, Zimmerman J, Damoiseaux R, Teitell MA, Koehler CM, Dev Cell. 2013 Apr 15;25(1):81-92

High-throughput screening of small molecules identifies hepcidin antagonists, Fung E, Sugianto P, Hsu J, Damoiseaux R, Ganz T, Nemeth E, Mol Pharmacol. 2013 Mar;83(3):681-90. doi: 10.1124/mol.112.083428. Epub 2013 Jan 4

Size of TiO(2) nanoparticles influences their phototoxicity: an in vitro investigation, Xiong S, George S, Ji Z, Lin S, Yu H, Damoiseaux R, France B, Ng KW, Loo SC, Arch Toxicol. 2013 Jan;87(1):99-109. doi: 10.1007/s00204-012-0912-5. Epub 2012 Aug 11

Size influences the cytotoxicity of poly (lactic-co-glycolic acid) (PLGA) and titanium dioxide (TiO(2)) nanoparticles, Xiong S, George S, Yu H, Damoiseaux R, France B, Ng KW, Loo JS, Arch Toxicol. 2013 Jun;87(6):1075-86. doi: 10.1007/s00204-012-0938-8. Epub 2012 Sep 16

Codelivery of an optimal drug/siRNA combination using mesoporous silica nanoparticles to overcome drug resistance in breast cancer in vitro and in vivo, Meng H, Mai WX, Zhang H, Xue M, Xia T, Lin S, Wang X, Zhao Y, Ji Z, Zink JI, Nel AE, ACS Nano. 2013 Feb 26;7(2):994-1005. doi: 10.1021/nn3044066. Epub 2013 Jan 4


High throughput screening for compounds that alter muscle cell glycosylation identifies new role for N-glycans in regulating sarcolemmal protein abundance and laminin binding, Cabrera PV, Pang M, Marshall JL, Kung R, Nelson SF, Stalnaker SH, Wells L, Crosbie-Watson RH, Baum LG, J Biol Chem. 2012 Jun 29;287(27):22759-70. doi: 10.1074/jbc.M111.334581. Epub 2012 May 8

Genome-wide assessment in Escherichia coli reveals time-dependent nanotoxicity paradigms, Reyes VC, Li M, Hoek EM, Mahendra S, Damoiseaux R, ACS Nano. 2012 Nov 27;6(11):9402-15. doi: 10.1021/nn302815w. Epub 2012 Oct 17

Dantrolene enhances antisense-mediated exon skipping in human and mouse models of duchenne muscular dystrophy, Kendall GC, Mokhonova EI, Moran M, Sejbuk NE, Wang DW, Silva O, Wang RT, Martinez L, Lu QL, Damoiseaux R, Spencer MJ, Nelson SF, Miceli MC, Sci Transl Med. 2012 Dec 12;4(164):164ra160

Zebrafish: An In Vivo Model for Nano EHS Studies, Lin S, Zhao Y, Nel AE, Lin S, Small. 2012 Dec 3. doi: 10.1002/smll.201202115

Zebrafish high-throughput screening to study the impact of dissolvable metal oxide nanoparticles on the hatching enzyme, ZHE1, Lin S, Zhao Y, Ji Z, Ear J, Chang CH, Zhang H, Low-Kam C, Yamada K, Meng H, Wang X, Liu R, Pokhrel S, Mädler L, Damoiseaux R, Xia T, Godwin HA, Lin S, Nel AE, Small. 2013 May 27;9(9-10):1776-85

High-throughput screening for bioactive molecules using primary cell culture of transgenic zebrafish embryos, Huang H, Lindgren A, Wu X, Liu NA, Lin S, Cell Rep. 2012 Sep 27;2(3):695-704

Inhibition of aminoacylase 3 protects rat brain cortex neuronal cells from the toxicity of 4-hydroxy-2-nonenal mercapturate and 4-hydroxy-2-nonenal, Tsirulnikov K, Abuladze N, Bragin A, Faull K, Cascio D, Damoiseaux R, Schibler MJ, Pushkin A, Toxicol Appl Pharmacol. 2012 Sep 15;263(3):303-14

Fluoxetine is a potent inhibitor of coxsackievirus replication, Zuo J, Quinn KK, Kye S, Cooper P, Damoiseaux R, Krogstad P, Antimicrob Agents Chemother. 2012 Sep;56(9):4838-44

Quantitative detection of PfHRP2 in saliva of malaria patients in the Philippines, Fung AO, Damoiseaux R, Grundeen S, Panes JL, Horton DH, Judy JW, Moore TB, Malar J. 2012 May 25;11:175.

Automated phenotype recognition for zebrafish embryo based in vivo high throughput toxicity screening of engineered nano-materials, Liu R, Lin S, Rallo R, Zhao Y, Damoiseaux R, Xia T, Lin S, Nel A, Cohen Y, PLoS One. 2012;7(4):e35014.

Use of metal oxide nanoparticle band gap to develop a predictive paradigm for oxidative stress and acute pulmonary inflammation, Zhang H, Ji Z, Xia T, Meng H, Low-Kam C, Liu R, Pokhrel S, Lin S, Wang X, Liao YP, Wang M, Li L, Rallo R, Damoiseaux R, Telesca D, Mädler L, Cohen Y, Zink JI, Nel AE, ACS Nano. 2012 May 22;6(5):4349-68

Combination of Rad001 (everolimus) and propachlor synergistically induces apoptosis through enhanced autophagy in prostate cancer cells, Tai S, Sun Y, Liu N, Ding B, Hsia E, Bhuta S, Thor RK, Damoiseaux R, Liang C, Huang J, Mol Cancer Ther. 2012 Jun;11(6):1320-31

Genome-wide Bacterial Toxicity Screening Uncovers the Mechanisms of Toxicity of Cationic Polystyrene Nanomaterials, Ivask A, Suarez E, Patel T, Boren D, Ji Z, Holden PA, Telesca D, Damoiseaux R, Bradley KA, Godwin HA, Environ Sci Technol. 2011 Dec


Role of Fe doping in tuning the band gap of TiO2 for the photo-oxidation-induced cytotoxicity paradigm. George S, Pokhrel S, Ji Z, Henderson BL, Xia T, Li L, Zink JI, Nel AE, Mädler L, J Am Chem Soc. 2011 Jul 27;133(29):11270-8

Synergistic Bactericidal Activity Ag-TiO2 Nanoparticles in Both Light and Dark Conditions, Li M, Noriega-Trevino ME, Nino-Martinez N, Marambio C, Wang J, Damoiseaux R, Ruiz F, Hoek EM, Environ Sci Technol. 2011 Aug 25

A molecular screening approach to identify and characterize inhibitors of glioblastoma multiforme stem cells, Visnyei K, Onodera H, Damoiseaux R, Saigusa K, Petrosyan S, De Vries D, Ferrari DB, Saxe J, Panosyan E, Masterman-Smith M, Mottahedeh J, Bradley KA, Huang J, Sabatti C, Nakano I, Kornblum HI, Mol Cancer Ther. 2011 Aug 22

High Content Screening in Zebrafish Speeds up Hazard Ranking of Transition Metal Oxide Nanoparticles, Lin S, Zhao Y, Xia T, Meng H, Ji Z, Liu R, George S, Xiong S, Wang X, Zhang H, Pokhrel S, Mädler L, Damoiseaux R, Lin S, Nel AE, ACS Nano, 2011 Aug 2

Seeing the Light: Luminescent Reporter Gene Assays, Miraglia L, King F, Damoiseaux R, Comb Chem High Throughput Screen. 2011 May 12

High throughput screening of small molecule libraries for modifiers of radiation responses, Kim K, Damoiseaux R, Norris AJ, Rivina L, Bradley K, Jung ME, Gatti RA, Schiestl RH, McBride WH, Int J Radiat Biol. 2011 Aug;87(8):839-4

Differential expression of syndecan-1 mediates cationic nanoparticle toxicity in undifferentiated versus differentiated normal human bronchial epithelial cells, Zhang H, Xia T, Meng H, Xue M, George S, Ji Z, Wang X, Liu R, Wang M, France B, Rallo R, Damoiseaux R, Cohen Y, Bradley KA, Zink JI, Nel AE, ACS Nano. 2011 Apr 26;5(4):2756-69

Use of a high-throughput screening approach coupled with in vivo zebrafish embryo screening to develop hazard ranking for engineered nanomaterials, George S, Xia T, Rallo R, Zhao Y, Ji Z, Lin S, Wang X, Zhang H, France B, Schoenfeld D, Damoiseaux R, Liu R, Lin S, Bradley KA, Cohen Y, Nel AE, ACS Nano. 2011 Mar 22;5(3):1805-17

No time to lose-high throughput screening to assess nanomaterial safety, Damoiseaux R, George S, Li M, Pokhrel S, Ji Z, France B, Xia T, Suarez E, Rallo R, Mädler L, Cohen Y, Hoek EM, Nel A, Nanoscale. 2011 Feb 7

Self-Organizing Map Analysis of Toxicity-Related Cell Signaling Pathways for Metal and Metal Oxide Nanoparticles, Rallo R, France B, Liu R, Nair S, George S, Damoiseaux R, Giralt F, Nel A, Bradley K, Cohen Y, Environ Sci Technol. 2011 Jan 20

Metabolic imaging allows early prediction of response to vandetanib, Walter MA, Benz MR, Hildebrandt IJ, Laing RE, Hartung V, Damoiseaux RD, Bockisch A, Phelps ME, Czernin J, Weber WA, J Nucl Med. 2011 Feb;52(2):231-40

Stability, bioavailability, and bacterial toxicity of ZnO and iron-doped ZnO nanoparticles in aquatic media.Li M, Pokhrel S, Jin X, Mädler L, Damoiseaux R, Hoek EM, Environ Sci Technol. 2011 Jan 15;45(2):755-61

Microfluidic image cytometry, Kamei K, Sun J, Tseng HR, Damoiseaux R, Methods Mol Biol. 2011;706:191-206


Substrate specificity of the TIM22 mitochondrial import pathway revealed with small molecule inhibitor of protein translocation,Hasson SA, Damoiseaux R, Glavin JD, Dabir DV, Walker SS, Koehler CM, Proc Natl Acad Sci U S A. 2010 May 25;107(21):9578-83. Epub 2010 May 10

A broad-spectrum antiviral targeting entry of enveloped viruses, Wolf MC, Freiberg AN, Zhang T, Akyol-Ataman Z, Grock A, Hong PW, Li J, Watson NF, Fang AQ, Aguilar HC, Porotto M, Honko AN, Damoiseaux R, Miller JP, Woodson SE, Chantasirivisal S, Fontanes V, Negrete OA, Krogstad P, Dasgupta A, Moscona A, Hensley LE, Whelan SP, Faull KF, Holbrook MR, Jung ME, Lee B, Proc Natl Acad Sci U S A. 2010 Feb 16;107(7):3157-62. Epub 2010 Jan 28

Substrate specificity of the TIM22 mitochondrial import pathway revealed with small molecule inhibitor of protein translocation,Hasson SA, Damoiseaux R, Glavin JD, Dabir DV, Walker SS, Koehler CM, Proc Natl Acad Sci U S A. 2010 May 25;107(21):9578-83. Epub 2010 May 10

A broad-spectrum antiviral targeting entry of enveloped viruses, Wolf MC, Freiberg AN, Zhang T, Akyol-Ataman Z, Grock A, Hong PW, Li J, Watson NF, Fang AQ, Aguilar HC, Porotto M, Honko AN, Damoiseaux R, Miller JP, Woodson SE, Chantasirivisal S, Fontanes V, Negrete OA, Krogstad P, Dasgupta A, Moscona A, Hensley LE, Whelan SP, Faull KF, Holbrook MR, Jung ME, Lee B, Proc Natl Acad Sci U S A. 2010 Feb 16;107(7):3157-62. Epub 2010 Jan 28

Integrated pathways for neutrophil recruitment and inflammation in leprosy, Lee DJ, Li H, Ochoa MT, Tanaka M, Carbone RJ, Damoiseaux R, Burdick A, Sarno EN, Rea TH, Modlin RL, J Infect Dis. 2010 Feb 15;201(4):558-69

Use of a rapid cytotoxicity screening approach to engineer a safer zinc oxide nanoparticle through iron doping, George S, Pokhrel S, Xia T, Gilbert B, Ji Z, Schowalter M, Rosenauer A, Damoiseaux R, Bradley KA, Mädler L, Nel AE, ACS Nano. 2010 Jan 26;4(1):15-29

Rottlerin stimulates apoptosis in pancreatic cancer cells through interactions with proteins of the Bcl-2 family, Ohno I, Eibl G, Odinokova I, Edderkaoui M, Damoiseaux RD, Yazbec M, Abrol R, Goddard WA 3rd, Yokosuka O, Pandol SJ, Gukovskaya AS, Am J Physiol Gastrointest Liver Physiol. 2010 Jan;298(1):G63-73


High-throughput screening identifies two classes of antibiotics as radioprotectors: tetracyclines and fluoroquinolones, Kim K, Pollard JM, Norris AJ, McDonald JT, Sun Y, Micewicz E, Pettijohn K, Damoiseaux R, Iwamoto KS, Sayre JW, Price BD, Gatti RA, McBride WH, Clin Cancer Res. 2009 Dec 1;15(23):7238-45

Discovery and structure-activity relationship analysis of Staphylococcus aureus sortase A inhibitors, Suree N, Yi SW, Thieu W, Marohn M, Damoiseaux R, Chan A, Jung ME, Clubb RT, Bioorg Med Chem. 2009 Oct 15;17(20):7174-85.

Nonaminoglycoside compounds induce readthrough of nonsense mutations, Du L, Damoiseaux R, Nahas S, Gao K, Hu H, Pollard JM, Goldstine J, Jung ME, Henning SM, Bertoni C, Gatti RA, J Exp Med. 2009 Sep 28;206(10):2285-97. Epub 2009 Sep 21.PMID: 19770270

Integrated chemical genomics reveals modifiers of survival in human embryonic stem cells, Damoiseaux R, Sherman SP, Alva JA, Peterson C, Pyle AD, Stem Cells. 2009 Mar;27(3):533-42

Ion channel and toxin measurement using a high throughput lipid membrane platformPoulos JL, Jeon TJ, Damoiseaux R, Gillespie EJ, Bradley KA, Schmidt JJ, Biosens Bioelectron. 2009 Feb 15;24(6):1806-10


A high-throughput screening strategy identifies cardiotonic steroids as alternative splicing modulators.Stoilov P, Lin CH, Damoiseaux R, Nikolic J, Black DL, Proc Natl Acad Sci U S A. 2008 Aug 12;105(32):11218-23

Regulation of Kaposi's sarcoma-associated herpesvirus reactivation by dopamine receptor-mediated signaling pathways, Lee S, Deng H, Yu F, Melega WP, Damoiseaux R, Bradley KA, Sun R, J Acquir Immune Defic Syndr. 2008 Aug 15;48(5):531-40. Erratum in: J Acquir Immune Defic Syndr. 2008 Oct 1;49(2):235


The small molecule harmine is an antidiabetic cell-type-specific regulator of PPARgamma expression, Waki H, Park KW, Mitro N, Pei L, Damoiseaux R, Wilpitz DC, Reue K, Saez E, Tontonoz P, Cell Metab. 2007 May;5(5):357-70

Amiodarone and bepridil inhibit anthrax toxin entry into host cells, Sanchez AM, Thomas D, Gillespie EJ, Damoiseaux R, Rogers J, Saxe JP, Huang J, Manchester M, Bradley KA, Antimicrob Agents Chemother. 2007 Jul;51(7):2403-11. Epub 2007 May 7.


Mycophenolic acid is a potent inhibitor of angiogenesis, Wu X, Zhong H, Song J, Damoiseaux R, Yang Z, Lin S, Arterioscler Thromb Vasc Biol. 2006 Oct;26(10):2414-6..

Cell-based chemical genetic screen identifies damnacanthal as an inhibitor of HIV-1 Vpr induced cell death, Kamata M, Wu RP, An DS, Saxe JP, Damoiseaux R, Phelps ME, Huang J, Chen IS, Biochem Biophys Res Commun. 2006 Sep 29;348(3):1101-6