The MSSR provides advanced, innovative instrumentation and services for the discovery and translation of small and large molecules into clinical candidates. MSSR services cover drug and target discovery, reagent and cell line generation as well as pre-clinical characterization of small and large molecules. With six integrated robotic screening systems, the MSSR has an industrial infrastructure that enables assay development and screening services. Available for screening are an updated in-house deck of over 300K extremely well curated compounds in plate formats up to 1536 with readouts ranging from any plate reader-based readout to confocal high content screening. Target discovery is performed using our unique 300k functional genomics probe set. Available are arrayed genome wide cDNA, siRNA and shRNA sets, as well as our new human genome wide arrayed CRISPR set. All reagents are in also available as single clone, custom arrayed or pooled format.

We are open to academic as well as industrial clients and have experience working with large pharmaceutical companies and smaller biotech companies alike.

Please do not let the cost of screening deter you from discussing your assay and interest with MSSR personnel. Limited funds may be available for proposed screens. A consultation is always free of charge as a courtesy to our drug discovery community.

Breakeven Internal Rate: $3105.94

JCCC Rate: $606.49

External Rate (OH): $4317.26

External Rate (OH + MU): $4317.26

Breakeven Internal Rate: $2704.00

JCCC Rate: $527.67

External Rate: $4317.26

Breakeven Internal Rate: $3800.86

JCCC Rate: $742.36

External Rate: $5283.20

We offer a full human genome wide set of gRNA’s. These are available as single clones, custom libraries both in viral and DNA forms – typically at a fraction of the price of commercial vendors. As a side note: We can also generate KO’s of interest for you in pertinent cell lines. We recommend to always use clonal lines for maximal experimental performance where possible. The pricing is identical to our assay development charges and especially interesting for JCCC members who are entitled to subsidized rates that are a fraction of the cost of outside companies.
We can also design gRNAs specific to your gene of interest. Our gRNAs are designed and validated to work with our genome editing tools to provide consistent high efficiency editing.We use high performance oligo manufacturing to design our guides. Whether you need an economical solution for routine editing tasks or you want to drive maximum editing efficiency, particularly in primary or stem cells, we have the tools required to introduce your specific edit in your cell line.

Breakeven Internal Rate: $59.43

JCCC Rate: $11.58

External Rate: $82.61

Request Clones

Breakeven Internal Rate: $2834.48

JCCC Rate: $553.24

External Rate: $3939.93

Breakeven Internal Rate: $2986.06

JCCC Rate: $583.12

External Rate: $4150.63

Breakeven Internal Rate: $2986.07

JCCC Rate: $583.13

External Rate: $4150.63

Breakeven Internal Rate: $ 2985.96

JCCC Rate: $586302

External Rate: $4150.49

Breakeven Internal Rate: $ 32.57

JCCC Rate: $ – 

External Rate: $ 45.28

Breakeven Internal Rate: $156.08

JCCC Rate: $30.55

External Rate: $216.95

HOURS OF OPERATION:

The facility is typically open for consultation from 9:00 am-5:00 pm, Monday through Friday. Screens may begin earlier and run longer than this allotted time as needed. The actual facility is open 24/7/365.

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